ea0007p185 | Reproduction | BES2004
Adams I
, Staunton B
, Gilson J
, Adams R
, Robinson J
, Atkin S
BackgroundSomatostatin (sst) acts via a series of 5 G-coupled receptors (sstr1-5) which control exocrine and endocrine secretions and also regulate cellular proliferation and apoptosis in many parts of the body. Recent experimental data suggests that sst plays a roles in ovarian function and the synthetic sstr agonists octreotide has been used in the treatment of polycystic ovarian syndrome. We have investigated the expression of somatostatin receptors (...